{"created":"2021-03-01T05:52:59.269612+00:00","id":1272,"links":{},"metadata":{"_buckets":{"deposit":"bb3cde38-4a97-4ce8-aa80-40925344176e"},"_deposit":{"id":"1272","owners":[],"pid":{"revision_id":0,"type":"depid","value":"1272"},"status":"published"},"_oai":{"id":"oai:repository.nii.ac.jp:00001272","sets":["136"]},"author_link":[],"control_number":"1272","item_5_biblio_info_30":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2013-11-13","bibliographicIssueDateType":"Issued"},"bibliographicPageEnd":"27","bibliographicPageStart":"1","bibliographic_titles":[{"bibliographic_title":"NIIテクニカル・レポート","bibliographic_titleLang":"ja"},{"bibliographic_title":"NII Technical Report","bibliographic_titleLang":"en"}]}]},"item_5_description_28":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The Cluster Newton method (CN method) has proved to be very efficient at finding multiple solutions to underdetermined inverse problems. In the case of pharmacokinetics, underdetermined inverse problems are often given extra constraints to restrain the variety of solutions. In this paper, we propose an algorithm based on the two parameters of the Beta distribution to find families of solution near a solution of interest. This allows for a much greater control of the variety of solutions that can be obtained with the CN method. In addition, this algorithm facilitates the task of obtaining pharmacologically feasible parameters. Moreover, we also make some improvements to the original CN method including an adaptive margin of error for the perturbation of the target values and the use of an analytical Jacobian in the resolution of the forward problem.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_5_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.20736/0000001272","subitem_identifier_reg_type":"JaLC"}]},"item_5_publisher_31":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"国立情報学研究所","subitem_publisher_language":"ja"}]},"item_5_source_id_32":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1346-5597","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Gaudreau, Philippe J.","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"速水, 謙","creatorNameLang":"ja"},{"creatorName":"Hayami, Ken","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"青木, 康憲","creatorNameLang":"ja"},{"creatorName":"Aoki, Yasunori","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"Safouhi, Hassan","creatorNameLang":"en"}]},{"creatorNames":[{"creatorName":"小長谷, 明彦","creatorNameLang":"ja"},{"creatorName":"Konagaya, Akihiko","creatorNameLang":"en"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-03-13"}],"displaytype":"detail","filename":"13-002E.pdf","filesize":[{"value":"1.0 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"NII Technical Report (NII-2013-002E)：Improvements to the Cluster Newton Method for Underdetermined Inverse Problems","url":"https://repository.nii.ac.jp/record/1272/files/13-002E.pdf"},"version_id":"dd52dc85-01f7-4d9d-b7ce-88c66d664cfc"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"テクニカルレポート","subitem_subject_language":"ja","subitem_subject_scheme":"Other"},{"subitem_subject":"Technical Report","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"NII Technical Report (NII-2013-002E)：Improvements to the Cluster Newton Method for Underdetermined Inverse Problems","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"NII Technical Report (NII-2013-002E)：Improvements to the Cluster Newton Method for Underdetermined Inverse Problems","subitem_title_language":"en"}]},"item_type_id":"5","owner":"1","path":["136"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2019-03-13"},"publish_date":"2019-03-13","publish_status":"0","recid":"1272","relation_version_is_last":true,"title":["NII Technical Report (NII-2013-002E)：Improvements to the Cluster Newton Method for Underdetermined Inverse Problems"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-01-11T02:37:23.641280+00:00"}